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Found 34 results
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Type
Year
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Melnick, Ari
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2009
Ci W
,
Polo JM
,
Cerchietti L
,
Shaknovich R
,
Wang L
,
Yang SNing
,
Ye K
,
Farinha P
,
Horsman DE
,
Gascoyne RD
et al.
. 2009.
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.
.
Blood. 113(22):5536-48.
Caldas-Lopes E
,
Cerchietti L
,
Ahn JH
,
Clement CC
,
Robles AI
,
Rodina A
,
Moulick K
,
Taldone T
,
Gozman A
,
Guo Y
et al.
. 2009.
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models.
.
Proc Natl Acad Sci U S A. 106(20):8368-73.
Cerchietti LC
,
Yang SNing
,
Shaknovich R
,
Hatzi K
,
Polo JM
,
Chadburn A
,
Dowdy SF
,
Melnick A
. 2009.
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.
.
Blood. 113(15):3397-405.
Cerchietti LC
,
Lopes EC
,
Yang SNing
,
Hatzi K
,
Bunting KL
,
Tsikitas LA
,
Mallik A
,
Robles AI
,
Walling J
,
Varticovski L
et al.
. 2009.
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.
.
Nat Med. 15(12):1369-76.
2008
Cerchietti LC
,
Polo JM
,
Da Silva GF
,
Farinha P
,
Shaknovich R
,
Gascoyne RD
,
Dowdy SF
,
Melnick A
. 2008.
Sequential transcription factor targeting for diffuse large B-cell lymphomas.
.
Cancer Res. 68(9):3361-9.
Ghetu AF
,
Corcoran CM
,
Cerchietti L
,
Bardwell VJ
,
Melnick A
,
Prive GG
. 2008.
Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.
.
Mol Cell. 29(3):384-91.
2007
Polo JM
,
Juszczynski P
,
Monti S
,
Cerchietti L
,
Ye K
,
Greally JM
,
Shipp M
,
Melnick A
. 2007.
Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.
.
Proc Natl Acad Sci U S A. 104(9):3207-12.
2006
Prokhortchouk A
,
Sansom O
,
Selfridge J
,
Caballero IM
,
Salozhin S
,
Aithozhina D
,
Cerchietti L
,
Meng FGuo
,
Augenlicht LH
,
Mariadason JM
et al.
. 2006.
Kaiso-deficient mice show resistance to intestinal cancer.
.
Mol Cell Biol. 26(1):199-208.
2004
Polo JM
,
Dell'Oso T
,
Ranuncolo SMaris
,
Cerchietti L
,
Beck D
,
Da Silva GF
,
Prive GG
,
Licht JD
,
Melnick A
. 2004.
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.
.
Nat Med. 10(12):1329-35.
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